Lab Safety Escape Room | Back to School Science Activity | Lab Safety Stations | Middle School & High School
Start the Year with Safe, Confident Scientists!
Ditch the lecture and turn your first lab safety lesson into a fun, interactive adventure! In this Lab Safety Escape Room, students rotate through 8 engaging stations as they investigate accidents, analyze Safety Data Sheets (SDS), identify proper PPE, choose the correct lab tools, evaluate lab behavior, analyze lab procedures, locate safety equipment, and reset a messy lab before earning their Lab Safety Clearance status and signing off on their lab safety contract.
Unlike traditional escape rooms, this activity uses a circular station design, allowing groups to begin at different stations, rotate independently and self-check. That means less waiting, less teacher management, and more student engagement! No locks required! Just envelopes and paper! Laminate your set to make it last for years and years!
Perfect for middle school and high school science classrooms, this activity gets students moving, collaborating, and thinking critically while learning the essential lab safety skills they'll use all year long.
WHAT'S INCLUDED in this SUPPLEMENTAL RESOURCE:
You Down With PPE? Yeah, You Know Me!: Learn why personal protective equipment matters.
Oops!... I Spilled It Again: Investigate a lab scenario and identify safety hazards.
What Does the SDS Say?: Use a Safety Data Sheet (SDS) to solve a real-world lab scenario.
Eye Can See Clearly Now: Locate the safety equipment in your own science classroom.
Stop! In the Name of Lab: Identify mistakes in a lab procedure before the experiment begins.
You're the Tool That I Want: Choose the correct equipment needed for a variety of lab investigations.
Bye Bye Bye!: Reset a messy lab station and decide what must be corrected before leaving the lab.
Don't Stand So Close to Me: Interview potential lab partners and identify the safest scientist to work beside.
→ Teacher setup guide with full-color photos
→ Student Lab Safety Clearance Card / response sheet
→ Circular station rotation (multiple starting points)
→ Lab Safety Contract
→ Teacher Guide & Answer keys
STUDENTS WILL:
- Rotate through the stations and solve clues based on the information provided
- Learn about lab safety procedures while participating in real-world scenarios.
- Review and sign a lab safety contract.
HERE'S WHY TEACHERS WILL LOVE THIS LAB SAFETY RESOURCE:
⭐ Keeps students actively engaged instead of sitting through another lab safety video and lecture.
⭐ Works with multiple groups at the same time using a circular station rotation.
⭐ Encourages collaboration, discussion, and critical thinking.
⭐ Reinforces real-world laboratory expectations in a memorable way.
⭐ Reusable year after year with minimal prep.
LAB SAFETY ESCAPE ROOM © Inside Out Science, 2025 to present. All rights reserved by author.





